Barely Significant
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Immunogenicity of a peptide-based anti-IgE conjugate vaccine in non-human primates.

Immun Inflamm Dis · 2016 · PMC4879460 · PMID 27957325

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a clear trendno p-value reported
Despite the lack of antigen dose effect on antibody titer and avidity, there was a clear trend for better functional responses (IgE lowering in blood) with higher antigen doses, suggesting that the assays for titer and avidity are not adequate predictors of anti‐IgE vaccine function.

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