The MYC 3' Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells.

Although it appeared that the frequency of MYC 5′ and 3′ interaction increased in 3′ WRE-Mut cells relative to control HCT116 cells, this difference did not reach statistical significance indicating that deleting TBE1 did not influence this chromatin conformation at the MYC locus in these cell populations ( Figure 3 A,B). 2.4.

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