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12-Lipoxygenase Inhibition on Microalbuminuria in Type-1 and Type-2 Diabetes Is Associated with Changes of Glomerular Angiotensin II Type 1 Receptor Related to Insulin Resistance.

Int J Mol Sci · 2016 · PMC4881510 · PMID 27164093

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12-LO inhibitor, cinnamyl-3,4-dihydroxy-α-cynanocinnamate (CDC), treatment slightly decreases blood glucose in STZ-induced type-1 diabetic rats compared to non-treated type-1 diabetic rats at the second and third week after STZ administration, but this did not reach statistical significance ( Figure 1 b).

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