Case control feasibility study assessing the association between severity of coronary artery disease with Glutathione Peroxidase-1 (GPX-1) and GPX-1 polymorphism (Pro198Leu).

BMC Cardiovasc Disord · 2016 · PMC4882825 · PMID 27229152

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showed a trendno p-value reported

GPX-1 activity did not show significant differences between two genotypes in both vessel and extent score groups, however the Pro198Leu (CT) genotype showed a trend of reduction in GPX-1 activity with increase severity in all three score groups indicating that T allele (Proline to Leucine substitution) was less responsive in stimulation of erythrocyte GPX-1 activity in patients with CAD.

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