Does quantitative lung SPECT detect lung abnormalities earlier than lung function tests? Results of a pilot study.

EJNMMI Res · 2014 · PMC4884006 · PMID 26055938

Europe PMC DOI

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quite significantno p-value reported

Since the outcome of a lung function test is a summation of the status of the whole lung, quite significant changes in lung function may occur before a deviation from the norm can be identified.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.