Barely Significant
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Leukocyte-Rich Platelet-Rich Plasma Injections Do Not Up-Modulate Intra-Articular Pro-Inflammatory Cytokines in the Osteoarthritic Knee.

PLoS One · 2016 · PMC4892682 · PMID 27258008

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nearly significantno p-value reported
The analysis of plasma and paired synovial fluid cytokine levels ( Table 3 ) showed a higher local concentration of IL-6, IL-8, and IL-13 (nearly significant in HA group) compared to systemic distribution, whereas IL-1b concentration was similar in plasma and synovial fluid ( Table 3 ).

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