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Blocking the tropomyosin receptor kinase A (TrkA) receptor inhibits pain behaviour in two rat models of osteoarthritis.

Ann Rheum Dis · 2016 · PMC4893148 · PMID 26286016

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Increases in paw withdrawal thresholds following AR786 administration were confirmed in MIA-induced OA using AUC analysis, whereas differences in MNX-induced OA did not reach statistical significance (see online supplementary figure S1).

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