JAK3-STAT pathway blocking benefits in experimental lupus nephritis.

Arthritis Res Ther · 2016 · PMC4898357 · PMID 27278657

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showed a trendno p-value reported

JAK3 inhibition showed a trend toward reducing all the evaluated Th1 cytokines, but it is noteworthy that there were significant reductions in the secretion of TNF-α, IFN-α, and IL-17.

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