Compared to the alkylating agent alone, we observed significant, or near-significant increases in growth delays for all three alkylating agents when combined with LND.
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Comparison of the Lonidamine Potentiated Effect of Nitrogen Mustard Alkylating Agents on the Systemic Treatment of DB-1 Human Melanoma Xenografts in Mice.
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The sentences
The mean difference in cell surviving fraction for LND + melphalan (10%, previously published results) versus melphalan alone (41%, previously published results) did not achieve significance [ 14 , 15 ].