Acute lung injury induced by whole gastric fluid: hepatic acute phase response contributes to increase lung antiprotease protection.

6a , the two- to three-fold mean increase in α1-AT mRNA, that was seen at 4 h and persisted during the first 24 h, did not reach statistical significance.

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Our results showed a highly significant enrichment in antiprotease content of the alveolar spaces, with a mean 58-fold increase in α1-AT activity and a mean 192-fold increase in α2-MG concentration in BALF.

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