Combined Inhibition of Complement and CD14 Attenuates Bacteria-Induced Inflammation in Human Whole Blood More Efficiently Than Antagonizing the Toll-like Receptor 4-MD2 Complex.

J Infect Dis · 2016 · PMC4907417 · PMID 26977050

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did not reach statistical significanceno p-value reported

The combination of anti-CD14 and compstatin Cp40 reduced the cytokine release by 60%–75%, also showing a tendency of stronger attenuation than the combination of eritoran and compstatin Cp40, although these differences did not reach statistical significance.

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