Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet.

Acta Neuropathol · 2016 · PMC4911374 · PMID 26971100

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

In quadriceps, PGC1α induction showed a trend for significance ( P = 0.08) at 40 days of age, suggesting that its dysregulation occurs very early in disease pathogenesis, with dysregulation increasing with disease progression.

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