established a positive correlation between autonomic neuropathy and peripheral neuropathy ( P = 0.00014); however, the further association between autonomic neuropathy and PVD failed to reach statistical significance.[ 45 ] In addition, a direct relationship of lower extremity arterial disease (LEAD) with T2DM was also documented by Chawla et al .
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Microvasular and macrovascular complications in diabetes mellitus: Distinct or continuum?
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