Identification of Poor-outcome Biliopancreatic Carcinoma Patients With Two-marker Signature Based on ATF6α and p-p38 "STARD Compliant".

Medicine (Baltimore) · 2015 · PMC4912267 · PMID 26559273

Europe PMC DOI

hedged sentences

0.0080

closest p · 0.2× alpha

0.1000

boldest claim

The sentences

highly significantP = 0.008actually significant

The 2-marker prognostic signature, based on ATF6α high and p-p38 low levels, showed highly significant association with time to recurrence ( P = 0.008) and a high trend with overall survival ( P = 0.062).

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showed a trendP = 0.1so close (0.05 < p ≤ 0.1)

Patients with high expression of ATF6α (ATF6α high ) showed a trend to decreased time to recurrence and overall survival ( P = 0.1 and P = 0.07, respectively) (data not shown).

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did not achieve significanceno p-value reported

Although ATF6α high and p-p38 low did not achieve significance in overall survival analysis, this result supports the role of this protein signature as a high-risk factor for these patients.

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