Targeting inflammation as a treatment modality for neuropathic pain in spinal cord injury: a randomized clinical trial.

J Neuroinflammation · 2016 · PMC4912827 · PMID 27316678

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.1000

boldest claim

The sentences

a trend towards significancep = 0.07so close (0.05 < p ≤ 0.1)

When assessing standardized beta weights, CES-D scores were not significant (beta = 0.244, p = 0.23), while IL-2 and PGE2 remained significant (beta = −0.731, p = 0.01; beta = 0.495, p = 0.03, respectively), and IFN-y showed a trend towards significance (beta = 0.462, p = 0.07).

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showed a trendp = 0.10so close (0.05 < p ≤ 0.1)

When analyzing each cytokine separately, the Mann-Whitney test indicated that the change scores (3 months − baseline) were significantly different between the treatment group and the control group for IFN-y ( U = 13.0, p = 0.01.), IL-1β ( U = 14.0, p = 0.01), and IL-2 ( U = 12.0, p = 0.01) and showed a trend for CRP ( U = 27.0, p = 0.10).

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