Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons.

Mol Psychiatry · 2016 · PMC4914410 · PMID 26830140

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We found a strong trend towards a reduction in the intensity of GAD67 staining in PV interneurons in adult MIA offspring ( Figure 3K&L ; GAD67 Mean Intensity (A.U.): Saline, 704.6±86.85, n=7; MIA, 518.2±37.32, n=7; t-test, p=0.07), suggesting that physiological changes in GABA synthesis may contribute to the deficit in GABAergic transmission from PV cells in MIA offspring.

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