Taken with the interactome observed for the 9 mRNA binding/splicing factors, there may be significant opportunity for overlap between these factors and other splicing factors in contributing to regulation of BMP4-dependent transcription.
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Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39.
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The sentences
While we found an apparent trend for increased expression of Sin3b-201 mRNA after RBM39 knockdown by qPCR (consistent with the results observed from RNA sequencing), the difference did not reach statistical significance.