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Phenotypic and functional testing of circulating regulatory T cells in advanced melanoma patients treated with neoadjuvant ipilimumab.

J Immunother Cancer · 2016 · PMC4915044 · PMID 27330811

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By testing Treg suppressive function, we observed trends of increase or decrease in suppressive function after ipi in individual patients that did not reach statistical significance over the entire group of patients.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.