Feasibility of establishing deletion of the late cornified envelope genes LCE3B and LCE3C as a susceptibility factor for psoriasis.

35%) although the difference did not reach statistical significance ( P = 0.507). de Cid et al . found a significantly higher frequency of D/D homozygotes among the patients (total D/D frequency, 0.45 in patients vs. 0.34 in controls; odds ratio = 2.04, 95% confidence interval = 1.59–2.62, P = 1.71e-08).[ 19 ] This was further confirmed by Hüffmeier et al . in individuals of German origin.[ 15 ] We did not find this difference when the psoriasis patients were compared to controls.

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