Does Inflammation Mediate the Obesity and BPH Relationship? An Epidemiologic Analysis of Body Composition and Inflammatory Markers in Blood, Urine, and Prostate Tissue, and the Relationship with Prostate Enlargement and Lower Urinary Tract Symptoms.

PLoS One · 2016 · PMC4918934 · PMID 27336586

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

marginally significantp = 0.08so close (0.05 < p ≤ 0.1)

Urinary markers of oxidative stress tended to be associated with a smaller prostate volume, with a marginally significant inverse association between urinary F2iP levels and prostate volume (p = 0.08).

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did not reach statistical significanceno p-value reported

Other systemic inflammatory markers such as IL-6 and IL-8 tended to also have inverse relationships with LUTS severity but did not reach statistical significance.

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