The Effect of Latency Reversal Agents on Primary CD8+ T Cells: Implications for Shock and Kill Strategies for Human Immunodeficiency Virus Eradication.

However, the co-culture of B/R-treated resting CD4 + T cells with stimulated CD8 + T cells did not result in a significant decrease in the amount of HIV-1 mRNA, although three of the six individuals showed a trend towards a decrease in the amount of cell-associated HIV-1 mRNA ( Fig. 1 B).

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