Finally, there were trends for increased eicosanoids in LFD-fed eWAT such as 15-HETE, 5-HETE and 9,10-DiHOME (metabolites that were significantly regulated in BMDMs by Fatp1 ), however these did not reach statistical significance in eWAT (data not shown). 3.6.
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Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation.
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The sentences
There was no Fatp1 genotype effect; however, insulin-stimulation reached significance in Fatp1B +/+ (P = 0.041) but failed to reach significance in Fatp1B −/− LFD-fed mice.