Homologous Recombination Repair Polymorphisms and the Risk for Osteosarcoma.

J Med Biochem · 2015 · PMC4922323 · PMID 28356832

Europe PMC DOI

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0.0720

closest p · 1.4× alpha

0.0720

boldest claim

The sentences

showed a trendP =0.072so close (0.05 < p ≤ 0.1)

The combination of both SNPs also showed a trend, albeit insignificant, towards decreased risk for developing osteosarcoma regardless the age at diagnosis ( P =0.072; OR=0.70; 95% CI=0.47–1.03), although individual XRCC3 rs861539 C>T and NBN rs1805794 G>C SNPs were not significantly associated with osteosarcoma in the whole cohort.

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