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Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis.

PLoS One · 2016 · PMC4922569 · PMID 27347680

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There was a trend for CVC7 and CVC20 to inhibit UUO-induced increases in the obstructed renal cortical mRNA expression of some fibrogenic genes; however, it did not reach statistical significance relative to UUO control.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.