Selective Brain-Targeted Antagonism of p38 MAPKα Reduces Hippocampal IL-1β Levels and Improves Morris Water Maze Performance in Aged Rats.

J Alzheimers Dis · 2015 · PMC4923728 · PMID 26401942

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

When normalized distance data were analyzed, ANOVA revealed a strong trend toward a main group effect ( p = 0.06) on day 17 and VX-745 1.5 mg/kg treated rats had significantly decreased distance values on day 17 when compared separately to vehicle treated aged rats (Dunnet’s post-hoc test p = 0.029; t -test: p = 0.012).

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