Another explanation is that there may be significant differences between cell lines that have the signature PAX-FOXO1 fusion (SJCRH30) [18] and those that do not (RD), which would actually be an important finding because those tumors are the most aggressive and difficult to treat.
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Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma Cells.
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The time for tumor tripling was increased in the Y15-treated tumors compared with vehicle-treated tumors but did not reach statistical significance (5.1 ± 1.8 days vs 6.3 ± 1.3 days, NS, vehicle vs Y15).