The propensity score–matched time-dependent modified Cox proportional analysis HRs were 0.646 (95% CI 0.567–0.736; P < 0.001) and 0.587 (95% CI 0.512–0.672; P < 0.001) for AChEIs cDDDs of 28–365 and >365, respectively, relative to no AChEIs use (<28 cDDDs) There was a significant trend toward risk reduction with increasing doses of AChEIs (P for trend < 0.001) ( Table 4 ).
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Association between acetylcholinesterase inhibitors and risk of stroke in patients with dementia.
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