approached significancep = 0.056
In the second year a significant effect of the type of response was observed before the “ram effect” (p<0.03) and paired comparison showed that oestradiol concentration at -16h before the “ram effect” was significantly greater in the “precocious” group ( Fig 2C ; 2.61±1.27 versus 0.82±0.16 pg/mL; p<0.03) and approached significance at -8h (3.02±0.81 versus 1.30±0.35 pg/mL; p = 0.056).