The expression of AQP1 in glomeruli of DM eMnSOD-Tg mice showed a trend towards being higher than that of non-DM eMnSOD-Tg mice, but it was not statistically significant ( Fig 3C and 3D ).
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Hyperglycemia Induces Cellular Hypoxia through Production of Mitochondrial ROS Followed by Suppression of Aquaporin-1.
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