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Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats.

Int J Nanomedicine · 2016 · PMC4935044 · PMID 27418824

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Likewise, only sham rats treated with positive liposomes presented a higher signal in lungs compared to neutral liposomes (positive: 7.230e+009 [6.750e+009, 5.480e+010] vs neutral: 2.865e+009 [5.670e+008, 3.970e+009], P <0.05), while the comparison with negative liposomes did not reach statistical significance (negative: 3.18e+009 [2.44e+009, 3.6e+009]; Figure 4D ).

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