Altered MicroRNA Expression Is Associated with Tumor Grade, Molecular Background and Outcome in Childhood Infratentorial Ependymoma.

PLoS One · 2016 · PMC4938415 · PMID 27390862

Europe PMC DOI

hedged sentences

0.0270

closest p · 0.5× alpha

0.0690

boldest claim

The sentences

a considerable trend toward significancep = 0.027actually significant

Moreover positive correlation for miR-106b and a considerable trend toward significance in case of miR-19a was noted in relation to EZH2 expression (r = 0.36, p = 0.027 and r = 0.32, p = 0.054 respectively) what altogether indicated for miR-17/92 and miR-106/25 cluster families as significant for PFA ependymal tumors ( Fig 4 ).

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did not reach statistical significancep = 0.069so close (0.05 < p ≤ 0.1)

Also higher LAMA2 expression was associated with poorer prognosis, although the effect did not reach statistical significance (HR = 0.39, 95%C = 0.14–1.07, p = 0.069) ( Fig 3C ).

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a certain trend toward significanceno p-value reported

The probability of death was significantly higher in samples with lower expression of LAMA2 although observed differences were not statistically significant (p = 0.069) but revealed a certain trend toward significance ( Fig 3C , Table 4 ).

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