Comparison of weekly administration of cisplatin versus three courses of cisplatin 100 mg/m(2) for definitive radiochemotherapy of locally advanced head-and-neck cancers.

Those characteristics found to be significant ( p < 0.006 after Bonferroni correction for multiple tests representing an alpha level of 0.05) or showed a trend ( p < 0.055) on univariate analyses were subsequently analyzed in a multivariate manner with the Cox proportional hazards model.

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In the multivariate analysis of LRC, radiochemotherapy regimen ( p = 0.008) and gender ( p = 0.003) were significant, whereas primary tumor site ( p = 0.16) did not achieve significance (Table 5 ).

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