Tryptophan catabolism in Pseudomonas aeruginosa and potential for inter-kingdom relationship.

Bacterial metabolites of the quinolinine pathway may interfere with the outcome of infection When assessing virulence of each strain through survival of mice during acute lung infection, we showed a trend toward decreased survival in mice infected with CHA∆kynU strain compared to those infected with CHA∆kynA strain ( p = 0063) (Fig. 7 ).

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