Association between FGF23, α-Klotho, and Cardiac Abnormalities among Patients with Various Chronic Kidney Disease Stages.

After adjustment for sex, age, and eGFR, corrected calcium, inorganic phosphate CRP, diuretic use model, systolic blood pressure, and history of hypertension (model 4), the association between the highest FGF23 tertile and LVH Association between the highest FGF23 and LVH was found to be borderline significant (P = 0.05).

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On the other hand, the correlation between α-Klotho and LVMI was significant among those with CKD stage G3a ( Fig 2C ), but that between α-Klotho and LVEF did not reach statistical significance among any of the CKD stage subgroups ( Fig 2D ).

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