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Individualized Angiotensin-Converting Enzyme (ACE)-Inhibitor Therapy in Stable Coronary Artery Disease Based on Clinical and Pharmacogenetic Determinants: The PERindopril GENEtic (PERGENE) Risk Model.

J Am Heart Assoc · 2016 · PMC4943245 · PMID 27021566

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12 The individual interaction terms of the 3 SNPs, however, did not reach statistical significance in that particular trial because of limited statistical power (replication could take place in 1051 patients only).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.