Adverse prognostic impact of the CpG island methylator phenotype in metastatic colorectal cancer.

Br J Cancer · 2016 · PMC4947699 · PMID 27310704

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showed a trendno p-value reported

In a recent exploratory analysis of patients with stage III CRC treated with 5-fluorouracil and leucovorin alone (FL) or irinotecan (IFL), CIMP-positive patients treated with IFL showed a trend towards increased OS compared with those treated with FL ( Shiovitz et al , 2014 ).

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