Analyses of all DMARD users revealed a similar risk among DMARD users compared to non-users in the period preceding the introduction of the anti-TNF to the market and a decreasing trend showing a lower risk among DMARD users in the following two periods.
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Hospitalization for musculoskeletal disorders in rheumatoid arthritis patients: a population-based study.
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The sentences
The authors reported similar tendency related to hospitalizations due to exacerbation of the rheumatic disease (21.9 versus 47.5/100 py, p <0.0001) and for orthopedic and surgical indications, however the latter analyses did not reach statistical significance [ 9 ].