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Fasting-Induced Changes in Hepatic P450 Mediated Drug Metabolism Are Largely Independent of the Constitutive Androstane Receptor CAR.

PLoS One · 2016 · PMC4951123 · PMID 27434302

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Cyp3a11-Midazolam Fasting increased Cyp3a11 mRNA expression although this did not reach statistical significance in the CAR -/- mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.