In mCC1-treated mice there was a strong trend towards a decrease in the percentage of CEACAM1 + B cell aggregates (84.4% ± 14.3%), while the percentage of overall CEACAM1 + infiltrates remained nearly unchanged (74.6% ± 12.5%) ( Supplementary Fig. 2D,E ).
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CEACAM1 mediates B cell aggregation in central nervous system autoimmunity.
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