As noted in the discovery cohort, a shorter median overall survival of 10.6 years was noted in HCMV positive participants (95% CI: 8.4–12.5) compared with 15.9 years (95% CI: 6.9–25.0) in HCMV negative participants although this did not reach statistical significance on either univariate (HR 1.45, 95% CI: 0.86–2.43; P = 0.158) or multivariate analysis (HR 0.96, 95% CI: 0.57–1.63; P = 0.882).
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Cytomegalovirus infection does not impact on survival or time to first treatment in patients with chronic lymphocytic leukemia.
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