The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.

Elife · 2016 · PMC4961458 · PMID 27410477

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did not reach statistical significanceno p-value reported

While the difference in reduction of FES uptake between the 10 mg/kg/day and 100 mg/kg/day treatment groups did not reach statistical significance, each dose resulted in a statistically lower FES uptake compared to that in vehicle-treated animals.

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