Differential Effectiveness of Clinically-Relevant Analgesics in a Rat Model of Chemotherapy-Induced Mucositis.

PLoS One · 2016 · PMC4963121 · PMID 27463799

Europe PMC DOI

hedged sentences

0.0004

closest p · 0.0× alpha

0.0004

boldest claim

The sentences

highly significantp = 0.0004actually significant

In the jejunum, both buprenorphine and tramadol caused a highly significant decrease in MPO activity in comparison with chemotherapy-treated control animals (53%, p = 0.0004 and 58%, p = 0.0001 respectively, Fig 2A ).

also in 132,142 other papers

showed a trendno p-value reported

However, tramadol as the most efficacious agent in reducing MPO, showed a trend towards restoration of villus height.

also in 53,322 other papers

failed to attain significanceno p-value reported

Tramadol had a lengthening effect on villus height when administered with 5-FU, although this failed to attain significance.

also in 59 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.