Similar to this, Mushtaq et al., who reviewed acidification among other extraction methods for metabolomics, could also not observe a clear trend since extraction with acidified solvents was seen as very efficient in one application while in another application extraction efficiency decreased when formic acid was added [ 30 ].
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Stable Isotope-Assisted Evaluation of Different Extraction Solvents for Untargeted Metabolomics of Plants.
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