Barely Significant
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Secukinumab, a novel anti-IL-17A antibody, shows low immunogenicity potential in human in vitro assays comparable to other marketed biotherapeutics with low clinical immunogenicity.

MAbs · 2016 · PMC4966846 · PMID 26817498

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Differences in cluster numbers among the other biotherapeutics were observed although these differences did not reach statistical significance, probably due to the limited number of donors in each set.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.