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Mild Alkalization Acutely Triggers the Warburg Effect by Enhancing Hexokinase Activity via Voltage-Dependent Anion Channel Binding.

PLoS One · 2016 · PMC4968818 · PMID 27479079

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HK-1 also showed a tendency of greater co-precipitation with VDAC by alkaline pH (143.1 ± 18.1%), although the difference did not reach statistical significance ( Fig 8A & 8B ).

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