Role of Inhaled Nitric Oxide in the Management of Severe Acute Respiratory Distress Syndrome.

Front Pediatr · 2016 · PMC4970488 · PMID 27532031

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did not reach statistical significanceno p-value reported

In 1998, the I-NO/PPHN study group showed that early use of iNO in term infants with persistent pulmonary hypertension (PPHN) had an acute and sustained improvement in oxygenation and a reduction in ECMO use that did not reach statistical significance ( 25 ).

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