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Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension.

PLoS One · 2016 · PMC4972384 · PMID 27487163

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showed a trendno p-value reported
We found that COL18A1 and APP mRNA and protein levels were significantly increased, while DSCR1 mRNA and protein levels showed a trend towards increased levels in fetal DS lungs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.