nearly significantP = 0.058
However, we found that the N/S in the internal branches of the highlander-specific haplogroups (1 ≤ ρ ≤ 4, N/S = 0.69) was nearly significant higher than that of all the 36,914 sequences (1 ≤ ρ ≤ 4, N/S = 0.47, P = 0.058) ( Fig. 3D , Table S6).