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A subpopulation of high IL-21-producing CD4(+) T cells in Peyer's Patches is induced by the microbiota and regulates germinal centers.

Sci Rep · 2016 · PMC4976330 · PMID 27499025

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A similar expression pattern was observed for IL-21 and ICOS, although the differences between Tfh populations did not reach statistical significance ( Supplementary Fig.

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