Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.

Fluids Barriers CNS · 2016 · PMC4977753 · PMID 27503326

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did not reach statistical significanceno p-value reported

7 c, d) (1.25 and 1.20-fold respectively) levels in the brain compared to vehicle-treated animals, although these values did not reach statistical significance.

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